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Cayman Chemical
Приєднався 1 лют 2011
Cayman Chemical
Helping Make Research Possible Since 1981
We supply scientists worldwide with the tools necessary to advance human and animal health. To help make your research possible, we create media that is instructive, educational, and beautiful.
Helping Make Research Possible Since 1981
We supply scientists worldwide with the tools necessary to advance human and animal health. To help make your research possible, we create media that is instructive, educational, and beautiful.
Delving into the World of Lysergamides: The Past, Present, and Future
Lysergamides are a class of alkaloids with a tetracyclic ergoline core structure. These compounds elicit their hallucinogenic properties by binding to and activating the serotonin 2A receptor. Variations to the ergoline core typically occur at three main regions of the core. These modifications give rise to some analogs with comparable efficacy to lysergic acid diethylamide (LSD). Listen to Camille Watson-Gooden and Danielle St. Germaine, scientists from Cayman’s Forensic Chemistry Division, discuss the history, modifications, fragmentation, and new emerging analogs of lysergamides.
Presented as part of the 2024 Current Trends in Seized Drug Analysis Symposium.
Presented as part of the 2024 Current Trends in Seized Drug Analysis Symposium.
Переглядів: 292
Відео
What’s New on the Designer Drug Scene Synthetic Cannabinoids, Precursors, and More
Переглядів 3174 місяці тому
As an important partner to the forensic community, Cayman Chemical is dedicated to the research, development, and production of a wide variety of research/analytical tools. It is our responsibility to monitor current trends and rapidly develop reference standards necessary for the early detection of NPS. Listen as Holly Pierzynski, Cayman’s Manager of Forensic Novel Psychoactive Substance Res...
Cayman Pharma Promotional video
Переглядів 1146 місяців тому
Headquartered in Ann Arbor, Michigan, Cayman Chemical Company has been supplying scientists worldwide with the resources necessary for advancing human and animal health since 1980. In 2004, Cayman Chemical began supporting the pharmaceutical industry with their first API, Latanoprost. Cayman Pharma (formerly Nerapharm) was acquired by Cayman Chemical in 2006, bringing with them substantial comm...
The Mind-Bending Mushroom: Expanding Consciousness of Psychedelic Alkaloids as Medicinal Tools
Переглядів 2677 місяців тому
Mushrooms have been used in medicinal and spiritual practices by Indigenous cultures around the world for several millennia. Because of renewed interest in entheogenic plant molecules as therapeutics, there is a large body of research building around psychedelic alkaloids found in the fungi kingdom. These fungi have captured our imagination and lie at the heart of scientific, health and even po...
What Can We Help You Discover?
Переглядів 5310 місяців тому
Our mission is to help make research possible. That starts by employing a talented and highly qualified group of experts to develop the tools to support research scientists across academic, biotechnology, and pharmaceutical institutions. Our scientists are experts in the synthesis, purification, and characterization of a wide-range of biochemicals. We are highly skilled in all aspects of assay ...
Isomers, Homologs, and Analogues of THC - Challenges for Identification and Separation of NPS
Переглядів 430Рік тому
Listen as Jeffrey B. Williams, Manager of Phytocannabinoid R&D at Cayman Chemical, discusses isomers, homologs, and analogues of tetrahydrocannabinol. Learn about some of the structural differences of new psychoactive products that are appearing from Cannabis and derived compounds of Cannabis, as well as associated challenges in identification and separation of these substances. Presented as pa...
Make, characterize and optimize LNPs with Nunchuck & Stunner
Переглядів 182Рік тому
Listen as Julie Rumble, PhD, Director of Immunology Services at Cayman Chemical, discusses the workflow for formulation, analysis, and testing of LNPs in multiple cell types. Presented by Unchained Labs and Fierce Biotech.
New Adversaries in the Opioid Crisis: The Nitazenes
Переглядів 4,8 тис.Рік тому
Listen as Danielle St. Germaine, a scientist from Cayman’s Forensic Chemistry Division, highlights the collaboration between Cayman’s Forensic Division and scientists at Ghent University in Belgium to profile a new synthetic opioid series which has emerged on the recreational drug scene. Watch this presentation to learn about the pharmacology of this class of very potent compounds that was publ...
The Magic and Chemistry Behind Psychedelic Mushrooms
Переглядів 8 тис.Рік тому
The revival of research into psychedelics as medicine has given rise to increased interest in psilocybin containing fungi. Psilocybin and its active metabolite psilocin are currently undergoing numerous clinical trials for various maladies such as depression, PTSD, addiction recovery, and smoking cessation among others. Given this renewed interest it is important to consider the chemistry behin...
A Review of Phencyclidine and Ketamine Analogues: Naming, Pharmacology, and EI-MS Interpretation
Переглядів 1,9 тис.2 роки тому
As an important partner to the forensic community, Cayman Chemical is dedicated to the research, development, and production of a wide variety of research and analytical tools. It is our responsibility to monitor current trends and rapidly develop standards necessary for the early detection of NPS. Listen as Danielle St. Germaine, a synthetic organic chemist in Cayman’s Forensic Chemistry Divis...
The NPS Reference Standard Manufacturer’s Role Within the Forensic Community
Переглядів 1652 роки тому
As an important partner to the forensic community, Cayman Chemical is dedicated to the research, development, and production of a wide variety of research and analytical tools. It is our responsibility to monitor current trends and rapidly develop standards necessary for the early detection of NPS. Listen as Dr. Donna Iula, Cayman’s Vice President of Forensic Chemistry, discusses Cayman’s workf...
Synthetic Cannabinoid News from 2021
Переглядів 3,7 тис.2 роки тому
As an important partner to the forensic community, Cayman Chemical is dedicated to the research, development, and production of a wide variety of research and analytical tools. It is our responsibility to monitor current trends and rapidly develop standards necessary for the early detection of NPS. Listen as Robert Schelkun, a synthetic organic chemist in Cayman’s Forensic Chemistry Division, d...
Understanding COVID's Long Game
Переглядів 1,6 тис.2 роки тому
In a growing number of people who contract COVID-19, symptoms persist long after the initial SARS-CoV-2 infection subsides. COVID-19 and long COVID patients display a variety of symptoms that reveal SARS-CoV-2’s versatility and its long-lasting impact on organ function. While this heterogeneity makes it difficult to study the disease, scientists apply every available technology to investigate t...
Synthesis, development, and naming of NPS reference materials
Переглядів 1,5 тис.2 роки тому
The rapid introduction of novel and diverse psychoactive substances on the designer drug scene continues to pose a challenge. Listen as Dr. Donna Iula, Cayman’s Vice President of Forensic Chemistry, describes the challenges of staying on top of this evolving market and what goes into the production of authentic reference standards. She will also discuss some of the latest NPS developments with ...
Selection and Characterization of hSTING-Agonists via in silico modeling and SPR
Переглядів 1072 роки тому
In this study, Cayman Chemical performed our established computer-aided screening techniques using Schrodinger to select hSTING agonists for further characterization via Surface Plasmon Resonance (SPR). We established a SPR platform to evaluate binding kinetics and affinity measurements for the agonists. Synthesized agonists such as canonical CDN (2’,3’ cGAMP), amidobenzimidazoles (diABZI agoni...
Recombinant SARS-CoV-2 Neutralizing Antibody Blocks Spike RBD-ACE2 Interaction; SPR Characterization
Переглядів 1282 роки тому
Recombinant SARS-CoV-2 Neutralizing Antibody Blocks Spike RBD-ACE2 Interaction; SPR Characterization
Psychedelic Targets Research & Development
Переглядів 4642 роки тому
Psychedelic Targets Research & Development
Trippy Medicine: Morning Glories, Magic Mushrooms, Spoiled Wheat, and Smoking Toads
Переглядів 6 тис.3 роки тому
Trippy Medicine: Morning Glories, Magic Mushrooms, Spoiled Wheat, and Smoking Toads
Production and Characterization of N- and C- Terminal Selenocysteine P
Переглядів 1263 роки тому
Production and Characterization of N- and C- Terminal Selenocysteine P
Nitazenes - Emerging Benzimidazole Opioids
Переглядів 11 тис.3 роки тому
Nitazenes - Emerging Benzimidazole Opioids
Development and Validation of a Novel cGAS Inhibitor Screening Assay
Переглядів 4383 роки тому
Development and Validation of a Novel cGAS Inhibitor Screening Assay
Development and Validation of a 2’3’ cGAMP ELISA
Переглядів 7403 роки тому
Development and Validation of a 2’3’ cGAMP ELISA
Cell Death Detection Tools: Finding Clues in Morphology and Biology
Переглядів 3803 роки тому
Cell Death Detection Tools: Finding Clues in Morphology and Biology
Racing against COVID-19: Drug and Vaccine Development
Переглядів 4073 роки тому
Racing against COVID-19: Drug and Vaccine Development
Nitazenes - Emerging Benzimidazole Opioids
Переглядів 10 тис.3 роки тому
Nitazenes - Emerging Benzimidazole Opioids
Improving MHC-associated peptide sequencing approaches for tumor antigen identification
Переглядів 19 тис.3 роки тому
Improving MHC-associated peptide sequencing approaches for tumor antigen identification
Immunopeptidome Profiling & Peptide Production for Immuno-Oncology Therapeutic Discovery
Переглядів 3323 роки тому
Immunopeptidome Profiling & Peptide Production for Immuno-Oncology Therapeutic Discovery
Tools for Characterizing Metabolic Change in Cell-Based Systems
Переглядів 29 тис.3 роки тому
Tools for Characterizing Metabolic Change in Cell-Based Systems
Very interesting! Especially your thoughts about 1D-LSD are really insightfull.
here is new 1T-LSD